Kinetics of Plasmid Dna and Cationic Liposome Complexation through in Line Microchannel Saxs Measurements

نویسندگان

  • T. A. Balbino
  • L. P. Cavalcanti
  • C. L. P. Oliveira
  • G. de La Torre
چکیده

In this work we report the structural liposome modifications during DNA complexation using Small Angle X-ray Scattering (SAXS) technique. We obtained in situ complexation using an in line microchannel SAXS sample holder coupled to a fed-batch reactor and thus we were able to determine the electronic density profile and other liposome parameters in the presence of DNA.

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تاریخ انتشار 2011